
卫丹,副研究员,硕士研究生导师,工学博士。目前主要从事“生物材料多重物理信号设计及其对细胞行为调控”的相关研究。基于功能分子改性、多肽修饰、活性分子复合等,建立了多种功能化生物活性凝胶材料体系,并探究其在细胞行为调控方面的应用;围绕细胞微环境的多重信号设计,建立一系列基于仿生基质构建的粘弹性、动态力学、拓扑信号、免疫微环境等基质信号调控体系,并探究其在组织再生诱导方面的应用;建立系列光、电、磁、热刺激响应性基质材料体系,并探究基质材料介导的物理信号刺激对神经诱导再生的调控作用与分子机制研究。主持国家自然科学基金、四川省自然科学基金、中国国家博士后基金等多项科研项目。发表论文80多篇,以第一或通讯作者在Advanced Functional Materials、Materials Horizons、Chemical Engineering Journal、Small、Acta Biomaterialia、Carbohydrate Polymers等期刊发表多篇论文。
主要研究方向:
1、生物材料多重物理信号(力、电、磁、热等)设计
2、基质微环境设计与细胞行为调控
3、中枢神经组织诱导再生
招生专业:生物医学工程
代表性论文专著:
[1] M. Zeng, J. Ding, Y. Tian, Y. Zhang, X. Liu, Z. Chen, J. Sun, C. Wu, H. Yin, D. Wei*, H. Fan*, Phase Separation Manipulated Gradient Conductivity for A High‐Precision Flexible Pressure Sensor, Advanced Functional Materials 34 (52), (2024), 2411390
[2] J. Ding, M. Zeng, Y. Tian, Z. Chen, Z. Qiao, Z. Xiao, C. Wu, D. Wei*, J. Sun, H. Fan*, Flexible silk-fibroin-based microelectrode arrays for high-resolution neural recording, Materials Horizons 11 (18), (2024), 4338-4347
[3] M. Zeng, J. Ding, Y. Tian, Y. Zhang, X. Liu, Z. Chen, J. Sun, C. Wu, H. Yin, D. Wei*, H. Fan*, Dopamine-integrated all-hydrogel multi-electrode arrays for neural activity recording, Materials Horizons 11 (24), (2024), 6423-6434
[4] D. Wei, M. Zeng, B. Su, Y. Zhang, J. Ding, C. Wu, J. Sun, L. Zhou, H. Yin, H. Fan*, Magnetic on-off manipulated matrix mechanic vibration to enhance cell clutches-reinforcement and Ca2+ influx facilitating BMSCs neural differentiation and TBI repair, Chemical Engineering Journal 484 (2024), 149521
[5] Z. Qiao, J. Ding, M. Yang, Y. Wang, T. Zhou, Y. Tian, M. Zeng, C. Wu, D. Wei*, J. Sun, H. Fan*, Red-light-excited TiO2/Bi2S3 heterojunction nanotubes and photoelectric hydrogels mediate epidermal-neural network reconstruction in deep burns, Acta Biomaterialia 184 (2024), 114-126
[6] Y. Zhang, B. Su, Y. Tian, Z. Yu, X. Wu, J. Ding, C. Wu, D. Wei*, H. Yin, J. Sun, H. Fan*, Magnetic manipulation of Fe3O4@ BaTiO3 nanochains to regulate extracellular topographical and electrical cues, Acta Biomaterialia 168 (2023), 470-483
[7] M. Zeng#, D. Wei#, J. Ding, Y. Tian, X. Wu, Z. Chen, C. Wu, J. Sun, H. Yin, H. Fan*, Dopamine induced multiple bonding in hyaluronic acid network to construct particle-free conductive hydrogel for reliable electro-biosensing, Carbohydrate Polymers 302 (2023), 120403
[8] J. Tang, C. Wu, Z. Qiao, J. Pi, Y. Zhang, F. Luo, J. Sun, D. Wei*, H. Fan*, A photoelectric effect integrated scaffold for the wireless regulation of nerve cellular behavior, Journal of Materials Chemistry B 10 (10), (2022), 1601-1611
[9] D. Wei, M. Zeng, B. Su, Y. Zhang, K. Wu, T. Zhou, C. Wu, J. Sun, H. Fan*, Bioactive cell niche mediating uniform thermal stimulus for BMSC neural differentiation through TRPV1 channel activation, Journal of Materials Chemistry B 11 (28), (2023), 6567-6580
[10] D. Wei, L. Charlton, A. Glidle, N. Qi, P.S. Dobson, M.J. Dalby, H. Fan*, H. Yin*, Dynamically modulated core–shell microfibers to study the effect of depth sensing of matrix stiffness on stem cell fate, ACS Applied Materials Interfaces 13 (32), (2021), 37997-38006
联系地址:四川大学望江校区生物材料楼706-1
Email:danwei@scu.edu.cn