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生物医学工程学院

副教授/副研究员/高级工程师

袁波

发布日期:2022年10月14日     编辑:     点击数:



袁波工学博士,中共党员。生物医学工程学院/国家生物医学材料工程技术研究中心副研究员、四川大学双百人才。担任国家药品监督管理局医疗器械技术审评中心咨询专家、增材制造医疗器械专业委员会委员等职务,还兼任Biomaterials Translational、Exploration等杂志青年编委。

主要从事组织诱导性生物材料研究,特别是骨诱导性生物材料的设计、制备与应用开发。近5年来,作为负责人主持国家自然科学基金、四川省重点研发项目、十三五/“十四五”国家重点研发计划子课题等国家及省部级项目11项;以第一或通讯作者在Science AdvancesBiomaterialsBioactive Materials等国际生物材料领域顶尖期刊发表高水平论文15篇,平均单篇影响因子大于10;申请国家发明专利10项,研究成果获四川大学2021年十大基础研究进展。


研究方向:

1. 骨诱导性生物材料及其植入器械的设计、制备及应用研究

2. 生物材料表面功能化设计及其对局部组织微环境的调控作用研究


代表性论文专著:

1. Bo Yuan, Pin Liu, Rui Zhao, Xiao Yang, Zhanwen Xiao, Kai Zhang,* Xiangdong Zhu,* Xingdong Zhang. Functionalized 3D-printed porous titanium scaffold induces in situ vascularized bone regeneration by orchestrating bone microenvironment, Journal of Materials Science & Technology, 2023, 153: 92-105

2. Bo Yuan, Yuxiang Zhang, Rui Zhao, Hai Lin, Xiao Yang, Xiangdong Zhu, Kai Zhang, Antonios G. Mikos, and Xingdong Zhang. A unique biomimetic modification endows polyetherketoneketone scaffold with osteoinductivity by activating cAMP/PKA signaling pathway, Science Advances, 2022, 8 (40): eabq7116.

3. Wanlu Zhao, Jinwei Yang,Yuhao Kang,Kaiyan Hu, Mingyue Jiao, Bing Zhao, Yanbiao Jiang, Chen Liu, Fengxing Ding, Bo Yuan,* Bin Ma,* Kai Zhang,* Antonios G. Mikos, and Xingdong Zhang. Animal Models of Rotator Cuff Injury and Repair: A Systematic Review, Tissue Engineering Part B: Reviews, 2022, doi.org/10.1089/ten.teb.2022.0034.

4. Bo Yuan, Hewei Chen, Rui Zhao, Xuangeng Deng, Guo Chen, Xiao Yang, Zhanwen Xiao, Antoniac Aurora, Bita Ana Iulia, Kai Zhang, Xiangdong Zhu*, Antoniac Vasile Iulian*, Hai Shen*, Xingdong Zhang, Construction of a magnesium hydroxide/graphene oxide/hydroxyapatite composite coating on Mg–Ca–Zn–Ag alloy to inhibit bacterial infection and promote bone regeneration. Bioactive Materials, 2022 (18): 354-367.

5. Jinwei Yang# Yuhao Kang# Wanlu Zhao#, Jia Jiang, Yanbiao Jiang, Bing Zhao, Mingyue Jiao, Bo Yuan*, Jinzhong Zhao*, Bin Ma*, Evaluation of patches for rotator cuff repair: a systematic review and meta-analysis based on animal studies, Bioactive Materials, 2021 (10): 474-491.

6. Yuxiang Zhang, Hongfeng Wu, Bo Yuan,* Xiangdong Zhu,* Kai Zhang and Xingdong Zhang, Enhanced osteogenic activity and antibacterial performance in vitro of polyetheretherketone by plasma-induced graft polymerization of acrylic acid and incorporation of zinc ions, Journal of Materials Chemistry B, 2021 9(36): 7506-7515.

7. Hewei Chen,# Bo Yuan,# Rui Zhao, Xiao Yang, Zhanwen Xiao, Antoniac Aurora, Bita Ana Iulia, Xiangdong Zhua,∗Antoniac Vasile Iulian,∗Xingdong Zhang, Evaluation on the corrosion resistance, antibacterial property and osteogenic activity of biodegradable Mg-Ca and Mg-Ca-Zn-Ag alloys, Journal of Magnesium and Alloys, DOI: 10.1016/j.jma.2021.05.013.

8. Bo Yuan, Linnan Wang, Rui Zhao, Xi Yang, Xiao Yang*, Xiangdong Zhu*, Limin Liu, Kai Zhang, Yueming Song, Xingdong Zhang. A biomimetically hierarchical polyetherketoneketone scaffold for osteoporotic bone repair, Science advances, 2020, 6(50): eabc4704.

9. Qinwen Cheng,# Bo Yuan,# Xuening Chen, Xiao Yang, Hai Lin, Xiangdong Zhu,* Kai Zhang* and Xingdong Zhang, Regulation of surface micro/nano structure and composition of polyetheretherketone and their influence on the behavior of MC3T3-E1 pre-osteoblasts, Journal of Materials Chemistry B, 2019, 7(37): 5713-5724.

10. Bo Yuan, Maria Grazia Raucci,* Yujiang Fan, Xiangdong Zhu, Xiao Yang,* Xingdong Zhang, Matteo Santinc and Luigi Ambrosio, Injectable strontium doped hydroxyapatite integrated with phosphoserine-tethered poly(epsilon -lysine) dendrons for osteoporotic bone defect repair, Journal of Materials Chemistry B, 2018, 6(47): 7974-7984.

11. Bo Yuan, Qinwen Chen, Rui Zhao, Xiangdong Zhu*, Xiao Yang, Xi Yang, Kai Zhang*, Yueming Song, Xingdong Zhang, Comparison of osteointegration property between PEKK and PEEK: effects of surface structure and chemistry, Biomaterials, 2018, 170: 116-126.

12. Bo Yuan, Yangmei Chen, Hai Lin, Yueming Song, Xi Yang, Hai Tang, En Xie, Tim Hsu, Xiao Yang, Xiangdong Zhu,* Kai Zhang,* and Xingdong Zhang, Processing and Properties of Bioactive Surface-Porous PEKK, ACS Biomater. Sci. Eng. 2016, 2(6): 977−986.


联系方式:

邮箱地址:scuyb@scu.edu.cn

办公地址:生物材料楼709



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